Assay Detail
Binding
CHEMBL5225702
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at dog SST2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Canis lupus familiaris |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Somatostatin receptor type 2 (CHEMBL5291563) ↗| Type | SINGLE PROTEIN |
| Organism | Canis lupus familiaris |
Publication
Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.18 | 8.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5267842 | PALTUSOTINE | 3.0 | 1 | 8.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5267842 | PALTUSOTINE | EC50 | = | 6.6 | nM | 8.18 |