Assay Detail
Binding
CHEMBL5226569
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of CerS2 in HPAC cells using DHSph as substrate by LC/MS/MS analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HPAC |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.67 | 5.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL314854 | FINGOLIMOD | 4.0 | 1 | 5.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL314854 | FINGOLIMOD | Ki | = | 2150.0 | nM | 5.67 |