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Assay Detail

CHEMBL5226577

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mouse CerS2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Ceramide synthase 2 (CHEMBL5291518)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.
Skácel J, Slusher BS, Tsukamoto T.
J Med Chem (2021) 64 : 279 -297
PubMed 33395289 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.16 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5268405 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5268405 IC50 = 7000.0 nM 5.16