Assay Detail
Binding
CHEMBL5226612
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat nSMase2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sphingomyelin phosphodiesterase 3 (CHEMBL4523130) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.22 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL491960 | CAMBINOL | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL491960 | CAMBINOL | IC50 | = | 6000.0 | nM | 5.22 |