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Assay Detail

CHEMBL5226620

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Mixed type inhibition of human recombinant glucocerebrosidase at pH 6.7
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.
Skácel J, Slusher BS, Tsukamoto T.
J Med Chem (2021) 64 : 279 -297
PubMed 33395289 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.09 5.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL153479 AMBROXOL 3.0 1 5.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL153479 AMBROXOL IC50 = 8100.0 nM 5.09