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Assay Detail

CHEMBL5226881

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human SW-620 cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SW-620
Confidence 1 — Organism
Curated By Autocuration

Target

SW-620 (CHEMBL612262)
Type CELL-LINE
Organism Homo sapiens

Publication

A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Phull MS, Jadav SS, Gundla R, Mainkar PS.
Eur J Med Chem (2021) 212 : 113149 -113149
PubMed 33445154 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.86 5.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL405862 NIGERICIN 1 5.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL405862 NIGERICIN IC50 = 1390.0 nM 5.86