Assay Detail
Functional
CHEMBL5226882
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anticancer activity against human KM12 cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KM12 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.07 | 5.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405862 | NIGERICIN | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405862 | NIGERICIN | IC50 | = | 8480.0 | nM | 5.07 |