Assay Detail
Functional
CHEMBL5226892
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Anticancer activity against human SW480 cells assessed as reduction in cell viability
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW480 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.94 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4248974 | — | — | 1 | 7.82 |
| CHEMBL5279880 | — | — | 1 | 6.32 |
| CHEMBL1459534 | — | — | 1 | 6.16 |
| CHEMBL5267289 | — | — | 1 | 4.97 |
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | — | 1 | 4.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4248974 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL5279880 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL1459534 | — | IC50 | = | 690.0 | nM | 6.16 |
| CHEMBL5267289 | — | IC50 | = | 10770.0 | nM | 4.97 |
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | IC50 | = | 35550.0 | nM | 4.45 |