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Assay Detail

CHEMBL5226955

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human UMSCC1 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type UMSCC1
Confidence 1 — Organism
Curated By Autocuration

Target

UMSCC1 (CHEMBL3707168)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation.
Bai R, Yao C, Zhong Z, Ge J, Bai Z, Ye X, Xie T, Xie Y.
Eur J Med Chem (2021) 213 : 113165 -113165
PubMed 33454546 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.86 5.06

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5270553 1 5.06
CHEMBL4203217 1 4.98
CHEMBL5274641 1 4.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5270553 IC50 = 8700.0 nM 5.06
CHEMBL4203217 IC50 = 10500.0 nM 4.98
CHEMBL5274641 IC50 = 28900.0 nM 4.54