Assay Detail
Functional
CHEMBL5227025
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against wild type SARS-CoV BJ01 infected in Vero E6 cells assessed as reduction in viral replication incubated for 64 hrs by MTT dye based ELISA assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Cell Type | Vero C1008 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV (CHEMBL4303836) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome-related coronavirus |
Publication
The race to treat COVID-19: Potential therapeutic agents for the prevention and treatment of SARS-CoV-2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.16 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5277868 | — | — | 1 | 5.35 |
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5277868 | — | EC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL151 | LUTEOLIN | EC50 | = | 10600.0 | nM | 4.97 |