Assay Detail
Functional
CHEMBL5227059
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Antiproliferative activity in human DMS-114 cells assessed as cell growth inhibition by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DMS-114 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nonpungent N-AVAM Capsaicin Analogues and Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.67 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL123254 | — | — | 1 | 4.82 |
| CHEMBL1672677 | — | — | 1 | 4.82 |
| CHEMBL1672680 | — | — | 1 | 4.37 |
| CHEMBL76903 | OLVANIL | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL123254 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1672677 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1672680 | — | IC50 | = | 43000.0 | nM | 4.37 |
| CHEMBL76903 | OLVANIL | IC50 | > | 50000.0 | nM | - |