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Assay Detail

CHEMBL5227179

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions.
Liao M, Zhang J, Wang G, Wang L, Liu J, Ouyang L, Liu B.
J Med Chem (2021) 64 : 2382 -2418
PubMed 33650861 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.18 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL190461 CANNABIDIOL 4.0 1 5.22
CHEMBL46740 BAZEDOXIFENE 4.0 1 5.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL190461 CANNABIDIOL IC50 = 6000.0 nM 5.22
CHEMBL46740 BAZEDOXIFENE IC50 = 7450.0 nM 5.13