Assay Detail
Functional
CHEMBL5227215
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Anticancer activity against human MDA-MB-436 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-436 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.20 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL41 | FLUOXETINE | 4.0 | 1 | 6.30 |
| CHEMBL4521985 | — | — | 1 | 5.30 |
| CHEMBL5273645 | — | — | 1 | 5.10 |
| CHEMBL5286755 | — | — | 1 | 5.06 |
| CHEMBL5275643 | — | — | 1 | 4.93 |
| CHEMBL1095284 | CEFATRIZINE | 2.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL41 | FLUOXETINE | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4521985 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL5273645 | — | IC50 | = | 7890.0 | nM | 5.10 |
| CHEMBL5286755 | — | IC50 | = | 8630.0 | nM | 5.06 |
| CHEMBL5275643 | — | IC50 | = | 11790.0 | nM | 4.93 |
| CHEMBL1095284 | CEFATRIZINE | IC50 | = | 30000.0 | nM | 4.52 |