Assay Detail
Functional
CHEMBL5227223
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Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.07 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1454946 | FLUBENDAZOLE | 2.0 | 1 | 6.60 |
| CHEMBL1208572 | SALINOMYCIN | 2.0 | 1 | 6.30 |
| CHEMBL3986860 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1454946 | FLUBENDAZOLE | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1208572 | SALINOMYCIN | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3986860 | — | IC50 | = | 5000.0 | nM | 5.30 |