Assay Detail
Functional
CHEMBL5227236
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Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.11 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5270793 | — | — | 1 | 8.21 |
| CHEMBL1078178 | MOMELOTINIB | 4.0 | 1 | 6.00 |
| CHEMBL404493 | — | — | 1 | 4.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5270793 | — | IC50 | = | 6.1 | nM | 8.21 |
| CHEMBL1078178 | MOMELOTINIB | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL404493 | — | IC50 | = | 74900.0 | nM | 4.13 |