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Assay Detail

CHEMBL5227375

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of beta catenin (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Catenin beta-1 (CHEMBL5866)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer.
Liu Z, Wang P, Wold EA, Song Q, Zhao C, Wang C, Zhou J.
J Med Chem (2021) 64 : 4257 -4288
PubMed 33822624 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2323032 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2323032 IC50 = 500.0 nM 6.30