Assay Detail
Binding
CHEMBL5227382
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to beta catenin (unknown origin) assessed as inhibition constant by alpha screen assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.52 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3589156 | — | — | 1 | 6.00 |
| CHEMBL3589012 | — | — | 1 | 5.77 |
| CHEMBL3589019 | — | — | 1 | 5.57 |
| CHEMBL3589160 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3589156 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL3589012 | — | Ki | = | 1700.0 | nM | 5.77 |
| CHEMBL3589019 | — | Ki | = | 2700.0 | nM | 5.57 |
| CHEMBL3589160 | — | Ki | = | 18000.0 | nM | 4.75 |