Assay Detail
Binding
CHEMBL5227480
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Inhibition of CDK9/Cyclin T (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Fused-azepinones: Emerging scaffolds of medicinal importance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.40 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296586 | KENPAULLONE | — | 1 | 7.19 |
| CHEMBL1782168 | — | — | 1 | 6.66 |
| CHEMBL1782169 | — | — | 1 | 6.62 |
| CHEMBL1782170 | — | — | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296586 | KENPAULLONE | IC50 | = | 64.0 | nM | 7.19 |
| CHEMBL1782168 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL1782169 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL1782170 | — | IC50 | = | 7400.0 | nM | 5.13 |