Assay Detail
Binding
CHEMBL5227490
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity against human integrin alphaVbeta3 expressed in CHO-K1 cells measured after 4 hrs by Cell adhesion assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Fused-azepinones: Emerging scaffolds of medicinal importance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.76 | 10.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5268482 | — | — | 1 | 10.40 |
| CHEMBL5287343 | — | — | 1 | 9.59 |
| CHEMBL404371 | — | — | 1 | 9.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5268482 | — | IC50 | = | 0.04 | nM | 10.40 |
| CHEMBL5287343 | — | IC50 | = | 0.26 | nM | 9.59 |
| CHEMBL404371 | — | IC50 | = | 0.5 | nM | 9.30 |