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Assay Detail

CHEMBL5227750

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against etoposide-resistant human KB cells assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KB
Confidence 1 — Organism
Curated By Autocuration

Target

KB (CHEMBL398)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy.
Shuai W, Wang G, Zhang Y, Bu F, Zhang S, Miller DD, Li W, Ouyang L, Wang Y.
J Med Chem (2021) 64 : 7963 -7990
PubMed 34101463 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.66 7.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4749443 1 7.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4749443 IC50 = 22.0 nM 7.66