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Assay Detail

CHEMBL5227764

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human ARD cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type ARD
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy.
Shuai W, Wang G, Zhang Y, Bu F, Zhang S, Miller DD, Li W, Ouyang L, Wang Y.
J Med Chem (2021) 64 : 7963 -7990
PubMed 34101463 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.51 7.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3774414 1 7.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3774414 IC50 = 31.0 nM 7.51