Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5227771

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MV4-11 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MV4-11
Confidence 1 — Organism
Curated By Autocuration

Target

MV4-11 (CHEMBL613835)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy.
Shuai W, Wang G, Zhang Y, Bu F, Zhang S, Miller DD, Li W, Ouyang L, Wang Y.
J Med Chem (2021) 64 : 7963 -7990
PubMed 34101463 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.51 7.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3774414 1 7.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3774414 IC50 = 31.0 nM 7.51