Assay Detail
Binding
CHEMBL5227884
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Inhibition of PP2A (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.17 | 10.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5276260 | — | — | 1 | 10.40 |
| CHEMBL430266 | CALYCULIN A | — | 1 | 8.82 |
| CHEMBL505512 | TAUTOMYCIN | — | 1 | 8.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5276260 | — | IC50 | = | 0.04 | nM | 10.40 |
| CHEMBL430266 | CALYCULIN A | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL505512 | TAUTOMYCIN | IC50 | = | 5.3 | nM | 8.28 |