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Assay Detail

CHEMBL5227925

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human NSCLC cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NSCLC
Confidence 1 — Organism
Curated By Autocuration

Target

NSCLC (CHEMBL612554)
Type CELL-LINE
Organism Homo sapiens

Publication

Camptothecin's journey from discovery to WHO Essential Medicine: Fifty years of promise.
Khaiwa N, Maarouf NR, Darwish MH, Alhamad DWM, Sebastian A, Hamad M, Omar HA, Orive G, Al-Tel TH.
Eur J Med Chem (2021) 223 : 113639 -113639
PubMed 34175539 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL307794 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL307794 EC50 = 1.0 nM 9.00