Assay Detail
Functional
CHEMBL5227950
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Antiproliferative activity against human MSTO-211H cells incubated for 72 hrs
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MSTO-211H |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Camptothecin's journey from discovery to WHO Essential Medicine: Fifty years of promise.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.71 | 8.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5278089 | — | — | 2 | 8.74 |
| CHEMBL5273769 | — | — | 2 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5278089 | — | IC50 | = | 1.8 | nM | 8.74 |
| CHEMBL5278089 | — | IC50 | = | 1.85 | nM | 8.73 |
| CHEMBL5273769 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL5273769 | — | IC50 | = | 2.2 | nM | 8.66 |