Assay Detail
Binding
CHEMBL5228224
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Agonist activity at RXRalpha (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting Nuclear Receptors in Neurodegeneration and Neuroinflammation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.53 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5280414 | — | — | 1 | 7.54 |
| CHEMBL1023 | BEXAROTENE | 4.0 | 1 | 7.48 |
| CHEMBL1545045 | VALERENIC ACID | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5280414 | — | EC50 | = | 29.0 | nM | 7.54 |
| CHEMBL1023 | BEXAROTENE | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL1545045 | VALERENIC ACID | EC50 | = | 27000.0 | nM | 4.57 |