Assay Detail
Binding
CHEMBL5228233
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inverse agonist activity at TLX (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Nuclear receptor subfamily 2 group E member 1 (CHEMBL1961788) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting Nuclear Receptors in Neurodegeneration and Neuroinflammation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5277896 | — | — | 1 | 6.70 |
| CHEMBL2385268 | — | — | 1 | 6.70 |
| CHEMBL81379 | RETINAL | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5277896 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL2385268 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL81379 | RETINAL | EC50 | = | 200.0 | nM | 6.70 |