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Assay Detail

CHEMBL5228617

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K562
Confidence 1 — Organism
Curated By Autocuration

Target

K562 (CHEMBL385)
Type CELL-LINE
Organism Homo sapiens

Publication

Molecular hybrids: A five-year survey on structures of multiple targeted hybrids of protein kinase inhibitors for cancer therapy.
Soltan OM, Shoman ME, Abdel-Aziz SA, Narumi A, Konno H, Abdel-Aziz M.
Eur J Med Chem (2021) 225 : 113768 -113768
PubMed 34450497 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.02 7.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5170300 1 7.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5170300 IC50 = 95.0 nM 7.02