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Assay Detail

CHEMBL5228958

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of USP7 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Ubiquitin carboxyl-terminal hydrolase 7 (CHEMBL2157850)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structure-Activity Relationship of USP5 Inhibitors.
Mann MK, Zepeda-Velázquez CA, González-Álvarez H, Dong A, Kiyota T, Aman AM, Loppnau P, Li Y, Wilson B, Arrowsmith CH, Al-Awar R, Harding RJ, Schapira M.
J Med Chem (2021) 64 : 15017 -15036
PubMed 34648286 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.16 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4303622 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4303622 EC50 = 6900.0 nM 5.16