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Assay Detail

CHEMBL5229037

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human Menin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Menin (CHEMBL1615381)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent Progress of Small Molecule Menin-MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia.
Lei H, Zhang SQ, Fan S, Bai HR, Zhao HY, Mao S, Xin M.
J Med Chem (2021) 64 : 15519 -15533
PubMed 34726905 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.48 8.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4435830 1 8.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4435830 IC50 = 3.3 nM 8.48