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Assay Detail

CHEMBL5229133

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PHD2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Egl nine homolog 1 (CHEMBL5697)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.
Perry GS, Das M, Woon ECY.
J Med Chem (2021) 64 : 16974 -17003
PubMed 34792334 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.32 5.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL426560 1 5.41
CHEMBL316034 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL426560 IC50 = 3900.0 nM 5.41
CHEMBL316034 IC50 = 6000.0 nM 5.22