Assay Detail
Binding
CHEMBL5229223
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human full length LRH1 transfected in human HeLa cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Nuclear receptor subfamily 5 group A member 2 (CHEMBL3544) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The Medicinal Chemistry and Therapeutic Potential of LRH-1 Modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.43 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1765959 | — | — | 1 | 5.96 |
| CHEMBL5272388 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1765959 | — | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL5272388 | — | EC50 | = | 13000.0 | nM | 4.89 |