Assay Detail
Binding
CHEMBL5229314
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human NTR1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pseudoprolines as stereoelectronically tunable proline isosteres.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.22 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL258221 | — | — | 1 | 10.10 |
| CHEMBL407196 | NEUROTENSIN | — | 1 | 9.80 |
| CHEMBL3622806 | — | — | 1 | 7.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL258221 | — | IC50 | = | 0.08 | nM | 10.10 |
| CHEMBL407196 | NEUROTENSIN | IC50 | = | 0.16 | nM | 9.80 |
| CHEMBL3622806 | — | IC50 | = | 17.5 | nM | 7.76 |