Assay Detail
Binding
CHEMBL5229434
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of fluormone pan-PPARgreen from GST-tagged human PPARgamma ligand binding domain by LanthaScreen TR-FRET competitive binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Alkaloids and Coumarins with Adiponectin-Secretion-Promoting Activities from the Leaves of <i>Orixa japonica</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.67 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | 4.0 | 1 | 6.52 |
| CHEMBL5268127 | — | — | 1 | 5.52 |
| CHEMBL2346913 | — | — | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL5268127 | — | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL2346913 | — | Ki | = | 10700.0 | nM | 4.97 |