Assay Detail
Binding
CHEMBL5229439
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at GST-tagged PPAR-gamma ligand binding domain (unknown origin) assessed as recruitment of fluorescein-labeled SRC3 coactivator peptide by LanthaScreen TR-FRET Coactivator assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Alkaloids and Coumarins with Adiponectin-Secretion-Promoting Activities from the Leaves of <i>Orixa japonica</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.14 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | 4.0 | 1 | 5.46 |
| CHEMBL5268127 | — | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | EC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5268127 | — | EC50 | = | 15500.0 | nM | 4.81 |