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Assay Detail

CHEMBL5229465

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human pulmonary fibroblast cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type Pulmonary fibroblast
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis, Optical Properties, and Antiproliferative Evaluation of NBD-Triterpene Fluorescent Probes.
Medina-O'Donnell M, Vega-Granados K, Martinez A, Sepúlveda MR, Molina-Bolívar JA, Álvarez de Cienfuegos L, Parra A, Reyes-Zurita FJ, Rivas F.
J Nat Prod (2023) 86 : 166 -175
PubMed 36542806 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.62 4.83

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5273267 1 4.83
CHEMBL5270287 1 4.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5273267 IC50 = 14800.0 nM 4.83
CHEMBL5270287 IC50 = 39700.0 nM 4.40