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Assay Detail

CHEMBL5230259

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at integrin CD11B/CD18 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Integrin alpha-M/beta-2 (CHEMBL2111362)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Recent advances in steroid amino acid conjugates: Old scaffolds with new dimensions.
Singla P, Salunke DB.
Eur J Med Chem (2020) 187 : 111909 -111909
PubMed 31830636 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.08 5.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5271349 1 5.19
CHEMBL5278431 1 4.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5271349 IC50 = 6500.0 nM 5.19
CHEMBL5278431 IC50 = 10900.0 nM 4.96