Assay Detail
Binding
CHEMBL5230442
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Inhibition of human recombinant ACE2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.41 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5278408 | — | — | 1 | 5.80 |
| CHEMBL5280105 | — | — | 1 | 5.01 |
| CHEMBL289277 | EMODIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5278408 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL5280105 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL289277 | EMODIN | IC50 | = | 200000.0 | nM | - |