Assay Detail
Binding
CHEMBL5230722
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK7 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A comprehensive insight on the recent development of Cyclic Dependent Kinase inhibitors as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.54 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1230607 | PHA-793887 | 1.0 | 1 | 8.00 |
| CHEMBL4297488 | CT-7001 | 2.0 | 1 | 7.40 |
| CHEMBL5273925 | — | — | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1230607 | PHA-793887 | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4297488 | CT-7001 | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL5273925 | — | IC50 | = | 62.0 | nM | 7.21 |