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Assay Detail

CHEMBL5230858

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human HBL-100 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type HBL-100
Confidence 1 — Organism
Curated By Autocuration

Target

HBL-100 (CHEMBL614811)
Type CELL-LINE
Organism Homo sapiens

Publication

Novel quinazoline-based EGFR kinase inhibitors: A review focussing on SAR and molecular docking studies (2015-2019).
Bhatia P, Sharma V, Alam O, Manaithiya A, Alam P, Kahksha, Alam MT, Imran M.
Eur J Med Chem (2020) 204 : 112640 -112640
PubMed 32739648 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5282557 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5282557 IC50 = 10000.0 nM 5.00