Assay Detail
Binding
CHEMBL5230967
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Inhibition of HDAC2 (unknown origin)
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 7.07 | 8.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5274330 | — | — | 1 | 8.94 |
| CHEMBL3329991 | — | — | 1 | 8.29 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 7.73 |
| CHEMBL5266413 | — | — | 1 | 7.52 |
| CHEMBL5283721 | — | — | 1 | 7.52 |
| CHEMBL5286638 | — | — | 1 | 7.07 |
| CHEMBL5273937 | — | — | 1 | 6.57 |
| CHEMBL5289084 | — | — | 1 | 6.04 |
| CHEMBL5266796 | — | — | 1 | 6.04 |
| CHEMBL5279416 | — | — | 1 | 6.04 |
| CHEMBL5281688 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5274330 | — | IC50 | = | 1.14 | nM | 8.94 |
| CHEMBL3329991 | — | IC50 | = | 5.13 | nM | 8.29 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 18.55 | nM | 7.73 |
| CHEMBL5266413 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL5283721 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL5286638 | — | IC50 | = | 86.0 | nM | 7.07 |
| CHEMBL5273937 | — | IC50 | = | 267.0 | nM | 6.57 |
| CHEMBL5289084 | — | IC50 | = | 910.0 | nM | 6.04 |
| CHEMBL5266796 | — | IC50 | = | 910.0 | nM | 6.04 |
| CHEMBL5279416 | — | IC50 | = | 910.0 | nM | 6.04 |
| CHEMBL5281688 | — | IC50 | = | 1000.0 | nM | 6.00 |