Assay Detail
Functional
CHEMBL5230970
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Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.47 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5287395 | — | — | 1 | 6.22 |
| CHEMBL5274330 | — | — | 1 | 6.21 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 5.87 |
| CHEMBL5288573 | — | — | 1 | 4.83 |
| CHEMBL5269957 | — | — | 1 | 4.83 |
| CHEMBL5279301 | — | — | 1 | 4.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5287395 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL5274330 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 1350.0 | nM | 5.87 |
| CHEMBL5288573 | — | IC50 | = | 14670.0 | nM | 4.83 |
| CHEMBL5269957 | — | IC50 | = | 14670.0 | nM | 4.83 |
| CHEMBL5279301 | — | IC50 | = | 14670.0 | nM | 4.83 |