Assay Detail
Functional
CHEMBL5230985
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Cytotoxicity against human 518A2 cells assessed as inhibition of cell growth by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | 518A2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.67 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5270399 | — | — | 1 | 7.75 |
| CHEMBL5274875 | — | — | 1 | 6.52 |
| CHEMBL5268263 | — | — | 1 | 6.52 |
| CHEMBL4438671 | — | — | 1 | 6.52 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5270399 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL5274875 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL5268263 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4438671 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 900.0 | nM | 6.05 |