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Assay Detail

CHEMBL5230987

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PANC-1
Confidence 1 — Organism
Curated By Autocuration

Target

PANC-1 (CHEMBL614139)
Type CELL-LINE
Organism Homo sapiens

Publication

Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Liu W, Liang Y, Si X.
Eur J Med Chem (2020) 205 : 112679 -112679
PubMed 32791404 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.40 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4438671 1 6.52
CHEMBL5274875 1 6.52
CHEMBL5268263 1 6.52
CHEMBL98 VORINOSTAT 4.0 1 6.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4438671 IC50 = 300.0 nM 6.52
CHEMBL5274875 IC50 = 300.0 nM 6.52
CHEMBL5268263 IC50 = 300.0 nM 6.52
CHEMBL98 VORINOSTAT IC50 = 900.0 nM 6.05