Assay Detail
Functional
CHEMBL5230989
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Cytotoxicity against human MCF7/Topo cells assessed as inhibition of cell growth by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7/Topo |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.40 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5268263 | — | — | 1 | 6.52 |
| CHEMBL4438671 | — | — | 1 | 6.52 |
| CHEMBL5274875 | — | — | 1 | 6.52 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5268263 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4438671 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL5274875 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 900.0 | nM | 6.05 |