Assay Detail
Functional
CHEMBL5230992
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Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by SRB assay
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.39 | 9.00 |
| GI50 | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1336 | SORAFENIB | 4.0 | 1 | 9.00 |
| CHEMBL5290567 | — | — | 1 | 6.80 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.37 |
| CHEMBL5274737 | — | — | 1 | - |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1336 | SORAFENIB | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL5290567 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL5274737 | — | GI50 | = | 24900.0 | nM | - |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | GI50 | = | 50200.0 | nM | - |