Assay Detail
Functional
CHEMBL5231024
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Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | ASPC1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.30 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5266413 | — | — | 1 | 7.30 |
| CHEMBL5283721 | — | — | 1 | 7.30 |
| CHEMBL3329991 | — | — | 1 | 6.31 |
| CHEMBL3342181 | — | — | 1 | 6.06 |
| CHEMBL5268365 | — | — | 1 | 6.06 |
| CHEMBL5271817 | — | — | 1 | 6.06 |
| CHEMBL3342182 | — | — | 1 | 6.06 |
| CHEMBL5272141 | — | — | 1 | 6.06 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 5.50 |
| CHEMBL5272150 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5266413 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL5283721 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3329991 | — | IC50 | = | 490.0 | nM | 6.31 |
| CHEMBL3342181 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL5268365 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL5271817 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL3342182 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL5272141 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL5272150 | — | IC50 | > | 3050.0 | nM | - |