Assay Detail
Functional
CHEMBL5231032
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Cytotoxicity against human SMMC-7721 cells assessed as inhibition of cell growth by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SMMC-7721 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.20 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4533956 | — | — | 1 | 5.80 |
| CHEMBL5273409 | — | — | 1 | 5.31 |
| CHEMBL5282167 | — | — | 1 | 5.31 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 5.26 |
| CHEMBL23293 | SALIRASIB | 2.0 | 1 | 4.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4533956 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL5273409 | — | IC50 | = | 4930.0 | nM | 5.31 |
| CHEMBL5282167 | — | IC50 | = | 4930.0 | nM | 5.31 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 5460.0 | nM | 5.26 |
| CHEMBL23293 | SALIRASIB | IC50 | = | 48600.0 | nM | 4.31 |