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Assay Detail

CHEMBL5231072

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PDE5 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

cGMP-specific 3',5'-cyclic phosphodiesterase (CHEMBL1827)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Liu W, Liang Y, Si X.
Eur J Med Chem (2020) 205 : 112679 -112679
PubMed 32791404 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.33 7.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5276050 1 7.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5276050 IC50 = 46.3 nM 7.33