Assay Detail
Binding
CHEMBL5231110
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of B-Raf V600E mutant (unknown origin) incubated for 120 mins in presence of ATP by ADP-Glo luminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase B-raf (CHEMBL5145) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Systemic review on B-Raf<sup>V600E</sup> mutation as potential therapeutic target for the treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.43 | 8.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5283675 | — | — | 1 | 8.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5283675 | — | IC50 | = | 3.7 | nM | 8.43 |